# Dense results

An agent that retrieves eight passages has to read eight passages, decide
which are on-topic, and do the synthesis itself — every time anyone asks.
Brain consolidates the sources behind a subject into one summary with a
citation per claim, so the answer arrives already made.

This page is the same query against the same index, with and without that
layer.

## The query

*"cyclooxygenase inflammation cancer"*

## Without the summary layer — eight fragments

Ranked document hits. Each is a real source; none is an answer.

```
1  Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
2  Tumor-associated macrophages and high COX-2 → poor prognosis
3  COX-2 inhibitors enable repeated vaccinia virus administration
4  PI3Ks qualify as drug targets for cancer, inflammation …   (loosely related)
5  Osteoarthritic cartilage degradation indicators …           (loosely related)
6  15-Hydroxyprostaglandin dehydrogenase down-regulated in colorectal cancer
7  Omega-3-derived lipid mediators
8  COPD, neutrophils, cigarette smoke and COX
```

Thousands of tokens, two of them off the point, and the synthesis is still
the model's job — repeated on every query that lands near this subject.

### The raw response

A live pull for `"interleukin-1b inflammasome"` on the same corpus — the rows
a plain vector store returns, documents and facts, no synthesis:

```json
[
  { "id": "700b960dd0a3aad0", "kind": "doc",  "score": 0.992,
    "title": "Human Monocytes Engage Alternative Inflammasome Pathway" },
  { "id": "df399593abc4edcb", "kind": "doc",  "score": 0.989,
    "title": "Inflammasome-induced IL-1β secretion in microglia" },
  { "id": "4e6192a75e2477bc", "kind": "fact", "score": 0.939,
    "title": "[fact] Inflammasomes are multiprotein complexes that li…" },
  { "id": "86ac2fbf338b865b", "kind": "fact", "score": 0.935,
    "title": "[fact] Cytokines downstream of inflammasome activation,…" }
]
```

Four rows to read and reconcile before answering anything.


## With the summary layer — one consolidated answer

The top result is a single entity summary, consolidated from **11 source
documents**, each claim carrying the source it came from:

```
Cyclooxygenase-2 (Cox-2) — an enzyme implicated in inflammatory and
pathological processes: viral clearance, lipid-mediator generation, and
cancer development.

- Viral clearance: Cox-2 inhibitors circumvent viral-clearance limits via
  neutralising antibodies                                        [cited]
- Lipid mediators: generates bioactive signals (15-epi-LX, 18R-HEPE) via
  NSAIDs + omega-3                                               [cited]
- Renal vasoconstriction                                         [cited]
- Cancer: survivin correlation                                   [cited]
- COPD airways                                                   [cited]
```

The agent cites this and stops. It also carries a small entity-relation
graph — cox-2 → survivin, PGE-2, arachidonic-acid, aspirin — so the next
question about a neighbouring subject starts from the relations rather
than another eight-document read.

### The raw response

The same live pull as above, unfiltered. Row 1 is the dense summary, above
every raw document and fact — and its `kind` says what it is, so a model can
prefer it deliberately rather than by luck:

```json
[
  { "id": "0a013be2e4b93400", "kind": "summary", "score": 0.997,
    "title": "[rule] interleukin-1b is a proinflammatory cytokine who…" },
  { "id": "700b960dd0a3aad0", "kind": "doc",     "score": 0.992,
    "title": "Human Monocytes Engage Alternative Inflammasome Pathway" },
  { "id": "df399593abc4edcb", "kind": "doc",     "score": 0.989,
    "title": "Inflammasome-induced IL-1β secretion in microglia" },
  { "id": "4e6192a75e2477bc", "kind": "fact",    "score": 0.939,
    "title": "[fact] Inflammasomes are multiprotein complexes that li…" },
  { "id": "86ac2fbf338b865b", "kind": "fact",    "score": 0.935,
    "title": "[fact] Cytokines downstream of inflammasome activation,…" }
]
```

Row order tells the story: the answer, then the primary sources it was built
from, then supporting facts.

### The raw document

Document `0a013be2e4b93400` — row 1 in full, consolidated from 7 sources:

```
interleukin-1b is a proinflammatory cytokine whose bioactivity is
controlled by activation of the inflammasome.

Major capabilities and subsystems
- proinflammatory cytokine, bioactivity controlled by inflammasome
  activation                                      [700b960dd0a3aad0]
- generated through NLRP3 inflammasome activation in Myelodysplastic
  Syndromes, driving clonal expansion and pyroptotic death
                                                  [1a48fcf7bb8cb4be]
- produced in human monocytes in response to LPS via an alternative
  inflammasome pathway                            [700b960dd0a3aad0]
- controlled in ILC2s in airway inflammation, interacting with IL-4
  and IL-12 to steer cell fate   [b82d5fcd36bb8472, 90250f9be040c89e]

Invariants / gotchas
- the LPS "alternative inflammasome" uses NLRP3-ASC-caspase-1 but is
  devoid of pyroptosome formation, pyroptosis and K⁺-efflux
  dependency                                      [df399593abc4edcb]
- microglial IL-1β secretion is only partially caspase-1/4/5-dependent
  vs hematopoietic macrophages                    [df399593abc4edcb]
```

The "invariants / gotchas" section carries the exceptions — which is where a
synthesis usually goes wrong.

### Relations

Every entity carries a typed relations graph, queryable on its own —
`t-cells` has 85 edges, `breast-cancer` 57. *Some* summaries, this one
included, also inline a machine-readable block of them:

```json
{ "relations": [
    { "target": "caspase-1",          "type": "part_of",         "confidence": 0.9 },
    { "target": "lipopolysaccharide", "type": "integrates_with", "confidence": 0.9 }
] }
```

## What was measured

On BEIR SciFact, a public 5,183-document biomedical benchmark corpus:

- **Entity summaries are 35% of top-10 results**, and the **rank-1 result
  for 25% of queries** — the dense answer surfaces, rather than sitting
  below the fragments it replaces.
- **nDCG@10 of 0.71**, against a BM25 baseline of 0.665 on the same corpus
  and queries. Consolidation does not cost retrieval quality.

The same corpus consolidates `interleukin-1b` from 7 documents and
`azacytidine` from 3. Consolidation is per entity, so the ratio follows how
much has been written about a subject — and so does quality. Thin input
shows: an entity with only a handful of sources can open by defining itself
in terms of itself, because there is not enough cross-document material to
say something denser.

## Provenance

Measured by Levirge's evaluation harness on BEIR SciFact, a public
biomedical benchmark corpus, 15 Aug 2026. Both result lists come from the
same index and the same query — the only variable is the summary layer.

The raw-response sections are a live pull for *"interleukin-1b
inflammasome"* on the same corpus, a second query, because it is the one we
hold verbatim payloads for. Titles are excerpted; the summary text is
verbatim apart from one unrelated line — a consolidation defect we logged
rather than quietly leave in the example.

The effect is a property of consolidation, not of this corpus: how dense
your answers get depends on how many sources say something about the same
subject.

## Try it

[Request access](/contact), then call `search_knowledge` against your own
Vault — the consolidated summaries are what it returns.
